Rabbit anti-Reticulon-3 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Reticulon-3 may be involved in membrane trafficking in the early secretory pathway. Reticulon-3 inhibits BACE1 activity and amyloid precursor protein processing. It may induce caspase-8 cascade and apoptosis and may favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, Reticulon-3 may be involved in the viral replication or pathogenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O95197].
Alternate Names
ASY interacting protein; ASYIP; HAP; homolog of ASY protein; neuroendocrine-specific protein-like 2; neuroendocrine-specific protein-like II; NSPL2; NSPLII; NSP-like protein 2; NSP-like protein II; reticulon-3; RTN3-A1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.