Rabbit anti-SMARCAD1/ETL1 Antibody Affinity Purified
Catalog #
SMARCAD1/ETL1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 976 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine,
Rat
Bovine,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAD1/ETL1 is a unique member of this family in that it contains two DEAD/H box motifs, and thus is also a member of the DEAD/H-box-containing helicase superfamily. The chromosomal position of SMARCAD1 has been mapped, and it resides in a region rich in breakpoints and deletions associated with several human diseases. It is suggested to play a role in genetic instability and development.
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1
Alternate Names
ADERM; ATP-dependent helicase 1; BASNS; ETL1; HEL1; hHEL1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1
Applications