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Rabbit anti-SNUPN Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
SNUPN
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 310 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to SNUPN immobilized on solid support.

The epitope recognized by A305-568A maps to a region between residue 310 to 360 of human Snurportin-1 using the numbering given in entry O95149.1 (GeneID 10073).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to SNUPN immobilized on solid support.

The epitope recognized by A305-568A-T maps to a region between residue 310 to 360 of human Snurportin-1 using the numbering given in entry O95149.1 (GeneID 10073).

Country of Origin
USA

Additional Product Information

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. Snurportin-1 (SNUPN) interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor [taken from NCBI Entrez Gene (Gene ID: 10073)].

10073
SNUPN
snurportin 1
O95149
Snurportin-1

Alternate Names

KPNBL; RNA U transporter 1; RNUT1; Snurportin1; snurportin-1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.