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Rabbit anti-STAT5b Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
STAT5b
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 737 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

10 µl (200 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Presumed Reactivity
Mouse, Pig, Bovine, Rat
Antigen Species
Human
Concentration
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to STAT5b immobilized on solid support.

The epitope recognized by A303-495A maps to a region between residue 737 and 787 of human Signal Transducer and Activator of Transcription 5B using the numbering given in entry NP_036580.2 (GeneID 6777).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to STAT5b immobilized on solid support.

The epitope recognized by A303-495A-T maps to a region between residue 737 and 787 of human Signal Transducer and Activator of Transcription 5B using the numbering given in entry NP_036580.2 (GeneID 6777).
Country of Origin
USA

Additional Product Information

Signal transducer and activator of transcription 5b (STAT5b) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression [taken from NCBI Entrez Gene (Gene ID: 6777)].

6777
STAT5B
signal transducer and activator of transcription 5B
P51692
Signal transducer and activator of transcription 5B

Alternate Names

signal transducer and activator of transcription 5B; STAT5; transcription factor STAT5B

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.