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Rabbit anti-STAT5b Recombinant Monoclonal Antibody [BLR146J]

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
STAT5b
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR146J
Format:
Whole IgG
Immunogen:
Between 737 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Purified
100 µl (50+ tests)

10 µl (5+ tests)

$127.00 $482.00
Qty:

Product Details

Specifications

Verified Reactivity
Mouse, Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Production Procedures
Recombinant antibody was purified from cell culture supernatant.

Immunogen was a peptide representing a region between residue 737 and the C-terminus (residue 787) of human Signal Transducer and Activator of Transcription 5B using the numbering given in entry NP_036580.2 (Gene ID 6777).
Country of Origin
USA

Additional Product Information

Signal transducer and activator of transcription 5b (STAT5b) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression [taken from NCBI Entrez Gene (Gene ID: 6777)].

6777
STAT5B
signal transducer and activator of transcription 5B
P51692
Signal transducer and activator of transcription 5B

Alternate Names

signal transducer and activator of transcription 5B; STAT5; transcription factor STAT5B

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.