Rabbit anti-STIM1 Antibody Affinity Purified
Catalog #
STIM1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 635 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine,
Rat
Bovine,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
Stromal interaction molecule 1 (STIM1) a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q13586].
Alternate Names
D11S4896E; GOK; IMD10; STRMK; stromal interaction molecule 1; TAM; TAM1
Applications