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Rabbit anti-SUPT5H Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
SUPT5H
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 50 and 100
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Orangutan, Mouse
Antigen Species
Human
Stock Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to SUPT5H immobilized on solid support.

The epitope recognized by A300-868A-T maps to a region between residue 50 and 100 of human Suppressor of Ty 5 Homolog using the numbering given in entry NP_003160.2 (GeneID 6829).

Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT5H is a subunit of the DRB sensitivity inducing factor (DSIF) along with SUPT4H that functions as a negative elongation factor. DSIF associates with RNA Pol II and may inhibit elongation by pausing and terminating RNA Pol II activity.

6829

SUPT5H

SPT5 homolog, DSIF elongation factor subunit

O00267

Transcription elongation factor SPT5

Alternate Names

DRB sensitivity-inducing factor 160 kDa subunit, DRB sensitivity-inducing factor large subunit, DSIF large subunit, DSIF p160, hSPT5, SPT5, SPT5H, suppressor of Ty 5 homolog, Tat-cotransactivator 1 protein, Tat-CT1, Tat-CT1 protein, transcription elongation factor SPT5

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE.

Citations (2)