Rabbit anti-TBK1 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
TBK1 is a member of the I-kappa-B kinase (IKK) family that plays a role in embryonic development and in the innate immune response. In response to viral infection, TBK1 activity induces transcription of genes such as IFN-gamma inducible protein (ip10), and interferon beta (ifnb). TBK1 is also implicated in the NF-kappa-B activation pathway which involves phosphorylation of I-kappaB proteins and the release and translocation of the NF-kappa-B complex to the nucleus.
Alternate Names
FTDALS4; IIAE8; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine-protein kinase TBK1; T2K; TANK-binding kinase 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.