Rabbit anti-Thrombomodulin Recombinant Monoclonal Antibody [BLR253L]
Catalog #
Thrombomodulin
Human
Flow Cyt
,ICC
,IHC
,IP
,WB
COMET™
Rabbit
Recombinant Monoclonal
BLR253L
Whole IgG
Residues 17-515 (ECD)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Recombinant antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing the extracellular domain of human Thrombomodulin (residues 17-515, NP_000352.1).
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07204].
Alternate Names
AHUS6; BDCA3; CD antigen CD141; CD141; CD141 antigen; fetomodulin; THPH12; THRM; thrombomodulin; TM
Applications