Rabbit anti-TRIP10/CIP4 Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by A301-185A-T maps to a region between residue 25 and 75 of human thyroid receptor interacting protein 10 (Cdc42-interacting protein 4) using the numbering given in entry AAM46851.1 (GeneID 9322).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to TRIP10/CIP4 immobilized on solid support.
The epitope recognized by A301-185A maps to a region between residue 25 and 75 of human thyroid receptor interacting protein 10 (Cdc42-interacting protein 4) using the numbering given in entry AAM46851.1 (GeneID 9322).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
Alternate Names
cdc42-interacting protein 4; CIP4; HSTP; protein Felic; salt tolerant protein; salt tolerator; STOT; STP; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.