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Rabbit anti-TRIP1/SUG1 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
TRIP1/SUG1
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
Pig, Bovine, Rat
Antigen Species
Human
Stock Concentration
40 µg/ml
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to TRIP1/SUG1 immobilized on solid support.

The epitope recognized by A300-791A-T maps to a region between residue 1 and 50 of human Thyroid Receptor Interactor 1 using the numbering given in entry NP_002796.4 (GeneID 5705).

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Gene & Protein Information

Thyroid receptor interacting protein 1 (TRIP1) was originally identified as a protein that interacts with the thyroid receptor and is homologous to the yeast SUG1 protein, a transcriptional coactivator. It was later identified as an ATPase subunit of the 26S proteasome, a multicatalytic proteinase complex, and has also been shown to associate with nuclear receptors and transcription factors. TRIP1/SUG1 may function to regulate transcription factor abundance by targeting them for proteasome degradation.

5705

PSMC5

proteasome 26S subunit, ATPase 5

P62195

26S protease regulatory subunit 8

Alternate Names

26S protease regulatory subunit 8, 26S proteasome AAA-ATPase subunit RPT6, 26S proteasome regulatory subunit 8, MSUG1 protein, p45, p45/SUG, proteasome (prosome, macropain) 26S subunit, ATPase, 5, proteasome 26S ATPase subunit 5, Proteasome 26S subunit ATPase 5, proteasome subunit p45, S8, SUG1, SUG-1, Tat-binding protein homolog 10, TBP10, testicular tissue protein Li 149, thyroid hormone receptor-interacting protein 1, thyroid receptor interactor 1, TRIP1

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.