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Rabbit anti-VTA1/LIP5 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
VTA1/LIP5
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 250 and 300
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to VTA1/LIP5 immobilized on solid support.

The epitope recognized by A304-829A-T maps to a region between residue 250 to 300 of human Vacuolar protein sorting-associated protein VTA1 homolog using the numbering given in entry Q9NP79.1 (GeneID 51534).

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Gene & Protein Information

VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NP79].

51534

VTA1

vesicle trafficking 1

Q9NP79

Vacuolar protein sorting-associated protein VTA1 h

Alternate Names

C6orf55, dopamine-responsive gene 1 protein, DRG1, DRG-1, homolog of mouse SKD1-binding protein 1, HSPC228, LIP5, LYST-interacting protein 5, My012, SBP1, SKD1-binding protein 1, vacuolar protein sorting-associated protein VTA1 homolog, vesicle (multivesicular body) trafficking 1, Vps20-associated 1 homolog

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.