AbNano™ VHH Naïve Library Data Pack
Advance your VHH discovery programs with a deeply characterized, fully natural camelid library designed for rapid hit finding across difficult protein targets. Built from 103 naïve llamas and alpacas and extensively sequenced, this library delivers high functional diversity with minimal bias, giving your team a robust starting point for therapeutic, diagnostic, and research applications. Unlock the full data pack to see detailed QC, panning results on INSR, EGFR, and PD‑L1, and practical guidance for integrating the library into your existing phage display workflows.
What You Get Inside
- Concise overview of the AbNano VHH Naïve Library: construction from 103 naïve llamas and alpacas, library size, and format (phage‑displayed, monovalent VHH).
- Detailed sequencing QC: V-gene usage, CDR3 length distribution, cluster density, and bias assessment to demonstrate an unbiased, transformation‑limited library with an estimated 6.48 × 10⁹ unique VHH clones.
- Application data: representative panning campaigns against INSR, EGFR, and PD‑L1, including hit rates, unique binder counts, and EC50 ranges in the 10⁻⁷–10⁻⁸ M range.
- Practical product information: physical characteristics (titer, volume, buffer, storage), phagemid backbone (pADL‑20c), and sequencing primer locations for your workflows.
Who Would Benefit
- Antibody discovery teams building VHH or other next generation formats (display, CAR‑T, bispecifics, or diagnostics).
- Scientists evaluating naïve vs immunized or synthetic VHH library strategies for broad target coverage.
- Biotech and pharma groups needing high‑diversity, well‑characterized starting material for rapid lead ID.
Related Resources
- [Product] AbNano VHH Naïve Library Product Details
- [Service] Custom VHH Discovery
- [Scientific Poster] AbNano VHH Naïve Library for Immuno-Oncology
