VHH Antibodies: Novel Engineering Strategies Beget Diverse Applications

Single-domain antibodies, also known as VHH, are a monomeric variable antibody domain. In research, therapeutic, and diagnostic applications, these single-domain antibodies have advantages over conventional antibodies. Applications of VHH include multiplex imaging, as a component of cell therapies or as a therapeutic modality themselves, and immunoassays for diagnostic and environmental monitoring assays.