Bethyl Laboratories
Rabbit anti-H2AX IHC Antibody Affinity Purified
Primary
Catalog #IHC-00008
TargetH2AX
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
H2AX is a member of the histone H2A family. The four core histones involved in the formation of the nucleosome structure of compacted chromatin are H2A, H2B, H3, and H4. H2AX may function to facilitate DNA repair, and recent studies have shown that H2AX is required for the maintenance of genomic stability. Gamma H2AX is the phosphorylated form of H2AX that results in response to DNA damage.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 93 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetH2AX
Antigen Species
Human
Gene ID3014
Gene Symbol
H2AFX
Gene Name
H2A histone family member X
Uniprot IDP16104
Protein Name
Histone H2AX
Alternate Names
H2A.X • H2A/X • H2AX • H2AX histone • histone H2A.x • histone H2AX
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to H2AX immobilized on solid support.
The epitope recognized by IHC-00008 maps to a portion of the C-terminus of human histone H2AX using the numbering given in entry NP 002096.1 (GeneID 3014).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00008Open
Product DatasheetPDF · IHC-00008 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00008 · Lot 1 (current lot)Open
Citations / Publications
Services
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