Bethyl Laboratories
Rabbit anti-USP7 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00018
TargetUSP7
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC, IHC-IF
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Product Description
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 7 (USP7) is a member of this family that has been shown to interact and stabilize p53.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetUSP7
Antigen Species
Human
Gene ID7874
Gene Symbol
USP7
Gene Name
ubiquitin specific peptidase 7
Uniprot IDQ93009
Protein Name
Ubiquitin carboxyl-terminal hydrolase 7
Alternate Names
deubiquitinating enzyme 7 • HAUSP • Herpes virus-associated ubiquitin-specific protease • Herpesvirus-associated ubiquitin-specific protease • TEF1 • ubiquitin carboxyl-terminal hydrolase 7 • ubiquitin specific peptidase 7 (herpes virus-associated) • ubiquitin specific protease 7 (herpes virus-associated) • ubiquitin thioesterase 7 • ubiquitin-specific-processing protease 7 • USP7
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to USP7 immobilized on solid support.
The epitope recognized by IHC-00018 maps to a region between residue 1 and 50 of human Ubiquitin Specific Peptidase 7 using the numbering given in entry NP_003461.1 (GeneID 7874).
Applications
Epitope exposure is not recommended.
Epitope exposure with citrate buffer will hinder staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00018Open
Product DatasheetPDF · IHC-00018 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00018 · Lot 1 (current lot)Open
Citations / Publications
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