Bethyl Laboratories
Rabbit anti-ASC2 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00019
TargetASC2
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Activating signal co-integrator 2 (ASC2) functions as a hormone-dependent transcriptional coactivator in cooperation with nuclear receptors such as steroids, retinoids, thyroid hormone, vitamin D3 and prostanoids. ASC2 also interacts with basal transcription factors and may also influence gene expression through its association with histone modifiers. ASC2 has been identified as an amplified gene in breast and other human cancers.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 2013 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetASC2
Antigen Species
Human
Gene ID23054
Gene Symbol
NCOA6
Gene Name
nuclear receptor coactivator 6
Uniprot IDQ14686
Protein Name
Nuclear receptor coactivator 6
Alternate Names
Activating signal cointegrator 2 • activating signal cointegrator-2 • AIB3 • amplified in breast cancer protein 3 • amplified in breast cancer-3 protein • ASC2 • ASC-2 • cancer-amplified transcriptional coactivator ASC-2 • NRC • NRC RAP250 • nuclear receptor coactivator 6 • nuclear receptor coactivator RAP250 • nuclear receptor-activating protein, 250 kDa • peroxisome proliferator-activated receptor interacting protein • Peroxisome proliferator-activated receptor-interacting protein • PPAR-interacting protein • PRIP • RAP250 • thyroid hormone receptor binding protein • Thyroid hormone receptor-binding protein • TRBP
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ASC2 immobilized on solid support.
The epitope recognized by IHC-00019 maps to a region between residue 2000 and the C-terminus (residue 2063) of human Activating Signal Cointegrator-2 using the numbering given in Swiss-Prot entry Q14686 (GeneID 23054).
Applications
Epitope exposure is recommended.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00019Open
Product DatasheetPDF · IHC-00019 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00019 · Lot 1 (current lot)Open
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