Bethyl Laboratories
Rabbit anti-NCOA2/SRC2 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00030
TargetNCOA2/SRC2
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Nuclear Receptor Coactivator 2 (NCOA2) is a member of the p160 family of nuclear receptor coactivators that also includes steroid receptor coactivator-1 (SRC-1) and p300/CBP-interacting protein (p/CIP). As Coactivators, this group of proteins helps recruit acetyltransferases and methyltransferases such as p300/CBP and CARM1 to facilitate chromatin remodeling and transcription factor recruitment, and to enhance gene expression. NCOA2 has been demonstrated to be important for the control of energy balance between white and brown adipose tissue.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1414 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetNCOA2/SRC2
Antigen Species
Human
Gene ID10499
Gene Symbol
NCOA2
Gene Name
nuclear receptor coactivator 2
Uniprot IDQ15596
Protein Name
Nuclear receptor coactivator 2
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to NCOA2/SRC2 immobilized on solid support.
The epitope recognized by IHC-00030 maps to a region between residue 1400 and the C-terminus (residue 1464) of human Nuclear Receptor Coactivator 2 using the numbering given in entry NP_006531.1 (GeneID 10499).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00030Open
Product DatasheetPDF · IHC-00030 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00030 · Lot 1 (current lot)Open
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