Rabbit anti-CARM1 IHC Antibody Affinity Purified

Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, has been shown to interact with and methylate RNA splicing factors such as CA150 that link transcription to splicing. In this context, CARM1 may be involved in spinal muscular atrophy pathogenesis. CARM1 has also been found to be a coactivator of the NFKappaB transcription factor and the androgen receptor.