Bethyl Laboratories
Rabbit anti-SMC3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00054
TargetSMC3
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
SMC3 (structural maintenance of chromosomes 3) is a component of the cohesin complex which is critical for precise duplication and segregation of chromosomes. SMC3 heterodimerizes with SMC1 and associates with two non-SMC subunits, Rad21/Scc1 and Scc3, to form the cohesin complex.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1167 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetSMC3
Antigen Species
Human
Gene ID9126
Gene Symbol
SMC3
Gene Name
structural maintenance of chromosomes 3
Uniprot IDQ9UQE7
Protein Name
Structural maintenance of chromosomes protein 3
Alternate Names
BAM • Bamacan • basement membrane-associated chondroitin proteoglycan • BMH • CDLS3 • Chondroitin sulfate proteoglycan 6 • chondroitin sulfate proteoglycan 6 (bamacan) • chromosome-associated polypeptide • CSPG6 • HCAP • SMC protein 3 • SMC-3 • SMC3L1 • structural maintenance of chromosomes protein 3
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to SMC3 immobilized on solid support.
The epitope recognized by IHC-00054 maps to a region between residue 1175 and C-termianl (residue 1217) of human Structural Maintenance of Chromosome 3 using the numbering given in entry NP_005436.1 (GeneID 9126).
Applications
Epitope exposure is recommended.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00054Open
Product DatasheetPDF · IHC-00054 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00054 · Lot 1 (current lot)Open
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