Bethyl Laboratories

Rabbit anti-HDAC1 IHC Antibody Affinity Purified

Primary
Catalog #IHC-00056
TargetHDAC1
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC, IHC-IF
Detection of human HDAC1 by immunohistochemistry.
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Product Description

Histone deacetylase 1 (HDAC1) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC1 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription.

Specifications

Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 432 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetHDAC1
Antigen Species
Human
Gene ID3065
Gene Symbol
HDAC1
Gene Name
histone deacetylase 1
Uniprot IDQ13547
Protein Name
Histone deacetylase 1
Alternate Names
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA

Production & Epitope

Antibody was affinity purified using an epitope specific to HDAC1 immobilized on solid support.

The epitope recognized by IHC-00056 maps to a region between residue 425 and the C-terminus (residue 482) of human Histone Deacetylase 1 using the numbering given in entry NP_004955.2 (GeneID 3065).

Applications

Epitope exposure is recommended.

Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500

Documents

Safety Data SheetPDF · IHC-00056Open
Product DatasheetPDF · IHC-00056 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00056 · Lot 1 (current lot)Open
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