Goat anti-ADAMTS13 Antibody Affinity Purified
Catalog #
ADAMTS13
Human
IP
,WB
Goat
Polyclonal
Whole IgG
Between 1377 and C-terminus
IgG
Agarose Immobilized
,Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
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Antibody was affinity purified using an epitope specific to ADAMTS13 immobilized on solid support.
The epitope recognized by A301-003A maps to a region between residue 1377 and the C-terminus (residue 1427) of human ADAM (a disintegrin-like and metalloprotease) metallopeptidase with thrombospondin type 1 motif, 13 using the numbering given in entry NP_620594.1 (GeneID 11093).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
USA
ADAMTS13 is part of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family that is responsible for cleaving von Willebrand Factor (vWF). ADAMTS13 is synthesized in the liver and secreted to the plasma. A deficiency of the ADAMTS13 protease activity results in unusually larger multimers of vWF and is associated with thrombotic thrombocytopenic purpura.
A disintegrin and metalloproteinase with thrombospondin motifs 13
Alternate Names