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Primary Antibodies

Mouse anti-CIP2A Monoclonal Antibody Affinity Purified [2A1-9A4]

Name: Mouse anti-CIP2A Monoclonal Antibody [2A1-9A4]
Brand: Bethyl Laboratories
SKU: A500-010A
Price: 127 USD

Bethyl Laboratories

Catalog #

Target:

CIP2A

Reactivity:

Human

Mouse

Applications:

Host:

Mouse

Clonality:

Monoclonal

Clone:

2A1-9A4

Format:

Whole IgG

Immunogen:

Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein

Isotype:

IgG1-kappa

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

100 µg (BSA-Free)

$127.00 $691.00

Qty:

Product Details

Specifications

Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration

40 µg/ml 1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Request Formulation Change

Tris-buffered Saline containing 0.09% Sodium Azide, BSA-Free

Request Formulation Change

Production Procedures

The immunogen was the amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein.

The hybridoma was grown in a bioreactor and the antibody was purified using a mouse immunoglobulin binding ligand.

Country of Origin

USA

Additional Product Information

CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.

Gene ID:

57650

Gene Symbol:

CIP2A

Gene Name:

cell proliferation regulating inhibitor of protein phosphatase 2A

Uniprot ID:

Q8TCG1

Protein Name:

Protein CIP2A

Alternate Names

cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; KIAA1524; p90; p90 autoantigen; protein CIP2A

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).

Mouse anti-CIP2A Monoclonal Antibody Affinity Purified [2A1-9A4]

Catalog #

CIP2A

Human

Mouse

IP

WB

Mouse

Monoclonal

2A1-9A4

Whole IgG

Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein

IgG1-kappa

Unconjugated

Purified

Mouse,

Human

Human

2 - 8 °C

1 year from date of receipt

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Tris-buffered Saline containing 0.09% Sodium Azide, BSA-Free

The immunogen was the amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein.The hybridoma was grown in a bioreactor and the antibody was purified using a mouse immunoglobulin binding ligand.

USA

57650

CIP2A

cell proliferation regulating inhibitor of protein phosphatase 2A

Q8TCG1

Protein CIP2A

cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; KIAA1524; p90; p90 autoantigen; protein CIP2A

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).

The immunogen was the amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein.

The hybridoma was grown in a bioreactor and the antibody was purified using a mouse immunoglobulin binding ligand.

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).