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Mouse anti-PCNA Monoclonal Antibody Purified [PC10]
Bethyl Laboratories
Catalog #
Validated
Target:
PCNA
Reactivity:
Human
,Mouse
Applications:
Flow Cyt
,ICC
,IHC
,IP
,WB
Platforms:
COMET™
Host:
Mouse
Clonality:
Monoclonal
Clone:
PC10
Format:
Whole IgG
Immunogen:
Recombinant rat PCNA
Isotype:
IgG2a
Conjugate:
Unconjugated
Purity:
Purified
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Human
Antigen Species
Human
Concentration
10 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
Request Formulation Change
Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide, BSA-Free
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Production Procedures
Monoclonal antibody was purified from cell culture supernatant.
Immunogen was recombinant rat PCNA
Monoclonal antibody was purified from cell culture supernatant.
Immunogen was recombinant rat PCNA.
Country of Origin
USA
Additional Product Information
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
Alternate Names
ATLD2; cyclin; DNA polymerase delta auxiliary protein; PCNA; proliferating cell nuclear antigen
Applications