Bethyl Laboratories
Rabbit anti-ABC50 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00588
TargetABC50
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
ATP-binding cassette sub-family F member 1 (ABCF1) is also known as ABC50 and belongs to the adenosine-triphosphate-binding cassette (ABC) family of transporters. ABC transporters are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and white. ABC50 is a member of the GCN20 subfamily. Unlike other ABC family members, ABC50 is not a membrane-spanning protein. ABC50 has been found to play a role in translation initiation and interacts with eIF2.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 795 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetABC50
Antigen Species
Human
Gene ID23
Gene Symbol
ABCF1
Gene Name
ATP binding cassette subfamily F member 1
Uniprot IDQ8NE71
Protein Name
ATP-binding cassette sub-family F member 1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ABC50 immobilized on solid support.
The epitope recognized by IHC-00588 maps to a region between residue 795 and 845 of human ATP-binding cassette 50 using the numbering given in entry NP_001020262.1 (GeneID 23).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00588Open
Product DatasheetPDF · IHC-00588 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00588 · Lot 1 (current lot)Open
Services
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