Bethyl Laboratories
Rabbit anti-ARA70 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00649
TargetARA70
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
ARA70 (androgen receptor-associated 70) was originally identified as part of chromosomal rearrangement involving the RET proto-oncogene. It was subsequently isolated in a two-hybrid screen as a ligand-dependent associated factor of the androgen receptor (AR). In addition to functioning as a co-activator of the AR, ARA70 has been found to function as a co-activator of the vitamin D receptor, estrogen receptor, PPARalpha, and PPARgamma.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 500 and 550
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
50 µg/ml
Target Identity
TargetARA70
Antigen Species
Human
Gene ID8031
Gene Symbol
NCOA4
Gene Name
nuclear receptor coactivator 4
Uniprot IDQ13772
Protein Name
Nuclear receptor coactivator 4
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ARA70 immobilized on solid support.
The epitope recognized by IHC-00649 maps to a region between residue 500 and 550 of human 70 kDa AR-activator (nuclear receptor coactivator 4) using the numbering given in entry NP_005428.1 (GeneID 8031).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00649Open
Product DatasheetPDF · IHC-00649 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00649 · Lot 1 (current lot)Open
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