Bethyl Laboratories
Rabbit anti-ARID4B IHC Antibody Affinity Purified
Primary
Catalog #IHC-00657
TargetARID4B
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IHC-IF
Image 1 of 1
local_shipping
Order within 5 hours and 7 minutes for shipment by today
Product Description
ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 125 and 175
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetARID4B
Antigen Species
Human
Gene ID51742
Gene Symbol
ARID4B
Gene Name
AT-rich interaction domain 4B
Uniprot IDQ4LE39
Protein Name
AT-rich interactive domain-containing protein 4B
Alternate Names
180 kDa Sin3-associated polypeptide • ARID domain-containing protein 4B • AT rich interactive domain 4B (RBP1-like) • AT-rich interactive domain-containing protein 4B • BCAA • BRCAA1 • breast cancer-associated antigen 1 • breast cancer-associated antigen BRCAA1 • breast carcinoma-associated antigen • histone deacetylase complex subunit SAP180 • Rb-binding protein homolog • RBBP1L1 • RBP1L1 • retinoblastoma-binding protein 1-like 1 • SAP180 • SIN3A-associated protein 180 • sin3-associated polypeptide p180
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ARID4B immobilized on solid support.
The epitope recognized by IHC-00657 maps to a region between residue 125 and 175 of human AT rich interactive domain 4B using the numbering given in entry NP_057458.4 (GeneID 51742).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00657Open
Product DatasheetPDF · IHC-00657 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00657 · Lot 1 (current lot)Open
Services
Antibody Conjugation
Antibody and conjugate formats developed together, built to your specification.
Request CustomizationCustom Monoclonal Antibody Discovery Services
Full custom monoclonal development, from immunization through validation.
Explore Monoclonal DevelopmentVHH Discovery
Single-domain antibodies for structurally difficult targets a conventional monoclonal can't reach.
Explore VHH DiscoveryResources
1