Bethyl Laboratories
Rabbit anti-ATRIP IHC Antibody Affinity Purified
Primary
Catalog #IHC-00451
TargetATRIP
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
ATRIP (ATR-interacting protein) forms a complex with the serine-threonine kinase ATR (ataxia-telangiectasia mutated rad-3 related) to function in the DNA damage response. Through its interaction with replication protein A (RPA), ATRIP aids the recruitment of ATR to regions of DNA damage. ATR-ATRIP interacts with and is regulated by Rad17 and the 9-1-1 complexes.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 75 and 125
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetATRIP
Antigen Species
Human
Gene ID84126
Gene Symbol
ATRIP
Gene Name
ATR interacting protein
Uniprot IDQ8WXE1
Protein Name
ATR-interacting protein
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ATRIP immobilized on solid support.
The epitope recognized by IHC-00451 maps to a region between residue 100 to 150 of human ATM and Rad3-related-interacting protein using the numbering given in entry NP_569055.1 (GeneID 84126).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00451Open
Product DatasheetPDF · IHC-00451 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00451 · Lot 1 (current lot)Open
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