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Rabbit anti-BCAR1/p130CAS IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
BCAR1/p130CAS
Reactivity:
Human
,Mouse
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 275 and 325
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Human
Presumed Reactivity
Monkey
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Country of Origin
USA
Additional Product Information
BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells.
Breast cancer anti-estrogen resistance protein 1
Alternate Names
BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; P130Cas
Applications