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Rabbit anti-Bcl-xL Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
Bcl-xL
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Presumed Reactivity
Mouse, Pig, Rat
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to Bcl-xL immobilized on solid support.

The epitope recognized by A300-284A maps to a region between residues 1 and 50 of human BCL2-like 1 using the numbering given in SwissProt entry Q07817 (GeneID 598).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to Bcl-xL immobilized on solid support.

The epitope recognized by A300-284A-T maps to a region between residues 1 and 50 of human BCL2-like 1 using the numbering given in SwissProt entry Q07817 (GeneID 598).
Country of Origin
USA

Additional Product Information

Bcl-xL is part of the BCL-2 family of proteins that regulates apoptosis and cell cycle control. Bcl-xL is the protein product of the larger alternatively spliced isoform of Bcl-x. Bcl-xL functions similarly to BCL2 in promoting cell survival and inhibiting proliferation by promoting G0 arrest. Bcl-xL is located in the outer mitochondrial membrane and promotes cell survival by preventing mitochondrial release of cytochrome c and caspase activation in response to apoptotic signals.

598
BCL2L1
BCL2 like 1
Q07817
Bcl-2-like protein 1

Alternate Names

apoptosis regulator Bcl-X; BCL2L; Bcl2-L-1; bcl-2-like protein 1; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).