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Rabbit anti-CARM1 IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
CARM1
Reactivity:
Human
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 558 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Mouse,
Dog,
Pig,
Bovine,
Monkey,
Rat
Dog,
Pig,
Bovine,
Monkey,
Rat
Pig,
Bovine,
Monkey,
Rat
Bovine,
Monkey,
Rat
Monkey,
Rat
Rat
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Country of Origin
USA
Additional Product Information
Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, has been shown to interact with and methylate RNA splicing factors such as CA150 that link transcription to splicing. In this context, CARM1 may be involved in spinal muscular atrophy pathogenesis. CARM1 has also been found to be a coactivator of the NFKappaB transcription factor and the androgen receptor.
Histone-arginine methyltransferase CARM1
Alternate Names
Coactivator-associated arginine methyltransferase 1; histone-arginine methyltransferase CARM1; PRMT4; protein arginine N-methyltransferase 4
Applications