Rabbit anti-CARMIL2 Antibody Affinity Purified
Catalog #
CARMIL2
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1385 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Human
2 - 8 °C
1 year from date of receipt
USA
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization. Plays a role in cell protrusion formations; involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations. Involved as well in cell migration and invadopodia formation during wound healing. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6F5E8].
F-actin-uncapping protein RLTPR
Alternate Names
Capping protein regulator and myosin 1 linker 2; capping protein, Arp2/3 and myosin-I linker protein 2; CARMIL2b; F-actin-uncapping protein RLTPR; IMD58; leucine rich repeat containing 16C; leucine-rich repeat-containing protein 16C; LRRC16C; RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing protein; RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein; RLTPR
Applications