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Rabbit anti-CCAR1 IHC Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
CCAR1
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
West Indian ocean coelacanth, Nile tilapia, Green anole, Japanese pufferfish, Zebra finch, Three-spined stickleback, Spotted green pufferfish, Turkey, White-tufted-ear marmoset, Tasmanian devil, Panda, Monkey, African elephant, Naked mole rat, Rabbit, Small-eared galago, Guinea pig_10141, Little brown bat, Gray short-tailed opossum, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Dog, Bovine, Chicken, Orangutan, Horse, Rat
Antigen Species
Human
Stock Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to CCAR1 immobilized on solid support.

The epitope recognized by IHC-00090-T maps to a region between residue 1 and 50 of human Cell-Cycle and Apoptosis Regulatory Protein 1 using the numbering given in TrEMBL entry Q6X935 (GeneID 55749).

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Gene & Protein Information

CCAR1 was identified as a perinuclear phosphoprotein that regulates apoptosis signals in response to chemotherapeutic agents. Induction of apoptosis by CCAR1 involves the epidermal growth factor receptor (EGFR), mitogen-activated protein kinase pathway and caspase-9 activation. CARP-1 has also been demonstrated as a suppressor of human breast cancer growth.

55749

CCAR1

cell division cycle and apoptosis regulator 1

Q8IX12

Cell division cycle and apoptosis regulator protei

Alternate Names

CARP-1, cell cycle and apoptosis regulatory protein 1, cell division cycle and apoptosis regulator protein 1, death inducer with SAP domain

Applications

Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated.