Rabbit anti-CD22 Recombinant Monoclonal Antibody [BLR320M]
Product Details
Specifications
Immunogen was a peptide representing a region between residue 750 and 800 of mouse B-cell receptor CD22 using the numbering given in entry NP_001036782.1 (Gene ID 12483).
Additional Product Information
CD22 mediates B-cell B-cell interactions and is involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins including CD45. It is involved in B cell activation; negative regulation of the B cell receptor signaling pathway; and regulation of endocytosis. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P20273].
Alternate Names
A530093D23;B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD antigen CD22;Lyb8;Lyb-8;sialic acid-binding Ig-like lectin 2;siglec-2;T-cell surface antigen Leu-14
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.