Rabbit anti-CD38 Recombinant Monoclonal Antibody [BLR123H]
Catalog #
CD38
Human
Flow Cyt
,ICC
,IHC
,IP
,WB
COMET™
Rabbit
Recombinant Monoclonal
BLR123H
Whole IgG
Residues 43-300 (ECD)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Recombinant antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing the extracellular domain of human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (aka CD38, residues 43-300, NP_001766.2).
USA
CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1) is a type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. The functional CD38 molecule is a dimer, with the central portion containing the catalytic site. CD38 is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [taken from NCBI Entrez Gene (Gene ID: 952)].
Alternate Names
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD antigen CD38; CD38 antigen (p45); cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; NAD(+) nucleosidase; T10
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