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Rabbit anti-CD47 Recombinant Monoclonal Antibody [BLR131H]
Bethyl Laboratories®
Catalog #
Validated
Target:
CD47
Reactivity:
Human
Applications:
ICC
,IHC
,WB
Platforms:
Simple Western
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR131H
Format:
Whole IgG
Immunogen:
residues 19-142 (ECD)
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Purified
100 µl (50+ tests)
10 µl (5+ tests)
100 µg (BSA-Free)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
50 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Additional Product Information
CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q08722].
Alternate Names
antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; CD antigen CD47; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 glycoprotein; IAP; integrin associated protein; Integrin-associated protein; integrin-associated signal transducer; leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen
Applications
