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Rabbit anti-Cdc42GAP IHC Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
Cdc42GAP
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
White-tufted-ear marmoset, Crab-eating macaque, Monkey, African elephant, Naked mole rat, Small-eared galago, Chinese hamster, Guinea pig_10141, Little brown bat, Thirteen-lined ground squirrel, Chimpanzee, Northern white-cheeked gibbon, Bovine, Orangutan, Rat
Antigen Species
Human
Stock Concentration
100 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to Cdc42GAP immobilized on solid support.

The epitope recognized by IHC-00610-T maps to a region between residue 1 and 50 of human CDC42 GTPase-activating protein using the numbering given in entry NP_004299.1 (GeneID 392).

Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

Cdc42 GTPase-activating protein (Cdc42GAP) is also known as p50RhoGAP and ARHGAP1. Cdc42GAP functions as a negative regulator of the Rho GTPase, Cdc42, by catalyzing the hydrolysis of GTP to GDP by Cdc42. Cdc42 activity is proposed to be involved in multiple cellular activities such as motility, survival, and genomic stability.

392

ARHGAP1

Rho GTPase activating protein 1

Q07960

Rho GTPase-activating protein 1

Alternate Names

CDC42 GTPase-activating protein, CDC42GAP, GTPase-activating protein rhoGAP, GTPase-activating protein rhoOGAP, GTPase-activating protein, Rho, 1, p50rhoGAP, p50-RhoGAP, rho GTPase-activating protein 1, RHOGAP, RHOGAP1, rho-related small GTPase protein activator, rho-type GTPase-activating protein 1

Applications

Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated.