/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Claudin-1 Recombinant Monoclonal Antibody [BLR094G]
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Primary Antibodies  

Rabbit anti-Claudin-1 Recombinant Monoclonal Antibody [BLR094G]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

Claudin-1

Reactivity:

Human

Applications:

ICC

,

IHC

,

IP

,

WB

Platforms:

COMET™

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR094G

Format:

Whole IgG

Immunogen:

between 161 and and 211 (C-term)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

100 µg (BSA-Free)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
500 µg/ml 1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide


Request Formulation Change

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


Request Formulation Change

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Additional Product Information

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. Claudin-1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95832].

9076

CLDN1

claudin 1

O95832

Claudin-1

Alternate Names

claudin-1; CLD1; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.