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Rabbit anti-CoCoA Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
CoCoA
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Orangutan
Antigen Species
Human
Stock Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to CoCoA immobilized on solid support.

The epitope recognized by A300-817A-T maps to a region between residue 1 and 50 of human Coiled-Coil Transcriptional Coactivator 1 using the numbering given in entry NP_065949.1 (GeneID 57658).

Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

CoCoA (coiled-coil coactivator) functions as a secondary coactivator for nuclear receptors and the LEF1/beta-catenin transcription factor. CoCoA is recruited to DNA bound nuclear receptors or factors by one of three p160 coactivator proteins that act as the primary coactivator. Through this interaction, CoCoA is able to contribute to transcriptional activation of target genes.

57658

CALCOCO1

calcium binding and coiled-coil domain 1

Q9P1Z2

Calcium-binding and coiled-coil domain-containing

Alternate Names

calcium-binding and coiled-coil domain-containing protein 1, calphoglin, Cocoa, coiled-coil coactivator protein, coiled-coil leucine zipper coactivator 1, inorganic pyrophosphatase activator, PP13275, sarcoma antigen NY-SAR-3

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE.