/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-CrkRS Antibody
NEW!
Primary Antibodies  

Rabbit anti-CrkRS Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (2)
Target:

CrkRS

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse,

Rat

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


Request Formulation Change
Additional Product Information

CrkRS (Cdc2-related kinase, arginine/serine-rich) is a Cdc-2 related kinase that contains an arginine- and serine-rich (SR) domain and has recently been reported to interact with cyclin L1 and L2. Since it has been discovered that CrkRs pairs with a cyclin partner, it has also been given the name CDK12. CrkRs localizes to nuclear speckles and immunoprecipitates with RNA polymerse II and the SF2/ASF splicing factor and is proposed to play a role in the regulation of alternative splicing.

51755

CDK12

cyclin dependent kinase 12

Q9NYV4

Cyclin-dependent kinase 12

Alternate Names

Cdc2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; cell division cycle 2-related protein kinase 7; cell division protein kinase 12; CRK7; CRKR; CRKRS; cyclin-dependent kinase 12; hCDK12

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.