Rabbit anti-CROP/Luc7A Antibody Affinity Purified
Catalog #
CROP/Luc7A
Human
IHC
,IP
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine
Bovine
Human
2 - 8 °C
1 year from date of receipt
USA
Cisplatin resistance-associated overexpressed protein (CROP) was originally cloned by differential display from cisplatin-resistant cells. It is an SR-related protein and the human homolog of the yeast protein, Luc7p. Luc7p is an essential protein involved in vegetative growth and 5’-splice recognition. CROP/Luc7a contains arginine- and glutamate-rich domains (RE domains) and arginine- and serine-rich domains (RS domains). It localizes to the nucleus and is distributed as speckles. CROP/Luc7a has been shown to interact with SF2/ASF, a protein involved in RNA splicing. Due to this association and the known function of its yeast homolog, CROP/Luc7a is proposed to play a role in RNA splicing.
Alternate Names
cAMP regulatory element-associated protein 1; cisplatin resistance-associated-overexpressed protein; CRA; CREAP-1; CRE-associated protein 1; CROP; hLuc7A; LUC7A; LUC7-like 3; luc7-like protein 3; OA48-18; okadaic acid-inducible phosphoprotein OA48-18
Applications