Bethyl Laboratories
Rabbit anti-CTNND1 Antibody Affinity Purified
Primary
Catalog #A300-978A
TargetCTNND1
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC, IP, WB
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Product Description
CTNND1 is an Armadillo repeat domain protein and member of the p120 protein family. The major function of CTNND1 involves the regulation of cadherins to influence cell-cell interactions. CTNND1 regulates cadherins by controlling cadherin turnover and/or trafficking. CTNND1 has also been found to play a role in the regulation of the actin cytoskeleton by modulating the activity of small GTPase Rho family members. CTNND1 is a substrate of the nonreceptor tyrosine kinase src and may play a role in the regulation of factors that regulate transcription.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 918 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
200 µg/ml
Target Identity
TargetCTNND1
Antigen Species
Human
Gene ID1500
Gene Symbol
CTNND1
Gene Name
catenin delta 1
Uniprot IDO60716
Protein Name
Catenin delta-1
Alternate Names
Product Information
Applications
IHC, IP, WB
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to CTNND1 immobilized on solid support.
The epitope recognized by A300-978A maps to a region between residue 891 and the C-terminus (residue 941) of human catenin (cadherin-associated protein), delta 1 using the numbering given in entry NP_001322.1 (GeneID 1500).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunohistochemistry (IHC)1:200 - 1:1000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Immunoprecipitation (IP)6 µg/mg lysate
Western Blot (WB)1:2000 - 1:10,000
Documents
Product DatasheetPDF · A300-978A · Lot 1 (current lot)Open
Product DatasheetPDF · A300-978A · Lot 1 (current lot)Open
Safety Data SheetPDF · A300-978AOpen
Services
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