Bethyl Laboratories
Rabbit anti-CTNND1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00523
TargetCTNND1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
CTNND1 is an Armadillo repeat domain protein and member of the p120 protein family. The major function of CTNND1 involves the regulation of cadherins to influence cell-cell interactions. CTNND1 regulates cadherins by controlling cadherin turnover and/or trafficking. CTNND1 has also been found to play a role in the regulation of the actin cytoskeleton by modulating the activity of small GTPase Rho family members. CTNND1 is a substrate of the nonreceptor tyrosine kinase src and may play a role in the regulation of factors that regulate transcription.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 75 and 125
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetCTNND1
Antigen Species
Human
Gene ID1500
Gene Symbol
CTNND1
Gene Name
catenin delta 1
Uniprot IDO60716
Protein Name
Catenin delta-1
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to CTNND1 immobilized on solid support.
The epitope recognized by IHC-00523 maps to a region between residue 75 and 125 of human catenin (cadherin-associated protein), delta 1 using the numbering given in entry NP_001322.1 (GeneID 1500).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00523Open
Product DatasheetPDF · IHC-00523 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00523 · Lot 1 (current lot)Open
Services
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