Bethyl Laboratories

Rabbit anti-Cyclin L1 IHC Antibody Affinity Purified

Primary
Catalog #IHC-00504
TargetCyclin L1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
Detection of human Cyclin L1 by immunohistochemistry.
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Product Description

Cyclin L1 is a member of the serine and arginine-rich family of proteins (SR proteins) which function as regulators of pre-mRNA splicing. Cyclin L2 has been reported to associate with RNA polymerase II and regulates the transcription and RNA processing of apoptosis-related factors, resulting in tumor cell growth inhibition and apoptosis.

Specifications

Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 350 and 400
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetCyclin L1
Antigen Species
Human
Gene ID57018
Gene Symbol
CCNL1
Gene Name
cyclin L1
Uniprot IDQ9UK58
Protein Name
Cyclin-L1
Alternate Names
ANIA6A  •  ania-6a  •  BM-001  •  cyclin L ania-6a  •  cyclin L gamma  •  cyclin-L  •  cyclin-L1  •  PRO1073
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA

Production & Epitope

Antibody was affinity purified using an epitope specific to Cyclin L1 immobilized on solid support.

The epitope recognized by IHC-00504 maps to a region between residue 350 and 400 of human cyclin L1 using the numbering given in entry NP_064703.1 (GeneID 57018).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.

Immunohistochemistry (IHC)1:100 - 1:500

Documents

Safety Data SheetPDF · IHC-00504Open
Product DatasheetPDF · IHC-00504 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00504 · Lot 1 (current lot)Open
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