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Rabbit anti-DCP1B Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
DCP1B
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 200 and 250
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

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Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Orangutan
Antigen Species
Human
Stock Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to DCP1B immobilized on solid support.

The epitope recognized by A303-640A-T maps to a region between residue 200 and 250 of human DCP1 Decapping Enzyme Homolog B using the numbering given in entry NP_689853.3 (GeneID 196513).

Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

mRNA-decapping enzyme 1B (DCP1B) may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IZD4].

196513

DCP1B

decapping mRNA 1B

Q8IZD4

mRNA-decapping enzyme 1B

Alternate Names

DCP1, DCP1 decapping enzyme homolog B, decapping enzyme hDcp1b, mRNA-decapping enzyme 1B

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE.