/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Dicer Antibody
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Primary Antibodies  

Rabbit anti-Dicer Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (4)
Target:

Dicer

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1175 and 1225

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Dicer is one of three human RNase III enzymes (Drosha, Dicer, and Argonaute) that plays a diverse role in the processing and maturation of RNA. Dicer is involved in processing pre-cursor mRNAs into both microRNAs (miRNAs) and short interfering RNAs (siRNAs) for the gene-silencing pathways of RNA interference (RNAi). Dicer interacts with Argonaute 2 (Ago2) and TRBP (TAR RNA-binding protein).

23405

DICER1

dicer 1, ribonuclease III

Q9UPY3

Endoribonuclease Dicer

Alternate Names

DCR1; Dicer; dicer 1, double-stranded RNA-specific endoribonuclease; dicer 1, ribonuclease type III; Dicer1, Dcr-1 homolog; Dicer1e; endoribonuclease Dicer; helicase MOI; helicase with RNAse motif; HERNA; K12H4.8-LIKE; MNG1; RMSE2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.