Bethyl Laboratories
Rabbit anti-DJ-1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00453
TargetDJ-1
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
DJ-1 appears to have a function in many biological processes. DJ-1 was first reported as an oncogene and then identified as a gene linked to Parkinson disease, a common neurodegenerative order. DJ-1 has also been observed to play a role in the fertilization process and to act as a sensor for oxidative stress.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 139 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
50 µg/ml
Target Identity
TargetDJ-1
Antigen Species
Human
Gene ID11315
Gene Symbol
PARK7
Gene Name
Parkinsonism associated deglycase
Uniprot IDQ99497
Protein Name
Protein deglycase DJ-1
Alternate Names
DJ1 • DJ-1 • epididymis secretory sperm binding protein Li 67p • GATD2 • HEL-S-67p • maillard deglycase • oncogene DJ1 • Parkinson disease (autosomal recessive, early onset) 7 • Parkinson disease protein 7 • parkinson protein 7 • Parkinsonism-associated deglycase • protein deglycase DJ-1 • protein DJ-1 • protein/nucleic acid deglycase DJ-1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to DJ-1 immobilized on solid support.
The epitope recognized by IHC-00453 maps to a region between residue 140 and the C-terminus (residue 189) of human DJ-1 (PARK7, Parkinson Disease 7) using the numbering given in entry NP_009193.2 (GeneID 11315 ).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00453Open
Product DatasheetPDF · IHC-00453 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00453 · Lot 1 (current lot)Open
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