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Rabbit anti-DYNC1I2 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
DYNC1I2
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Bovine, Orangutan
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to DYNC1I2 immobilized on solid support.

The epitope recognized by A304-528A-T maps to a region between residue 1 to 50 of human Dynein, Cytoplasmic 1, Intermediate Chain 2 using the numbering given in entry NP_001369.1 (GeneID 1781).

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Gene & Protein Information

Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. DYNC1I2 is involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13409].

1781

DYNC1I2

dynein cytoplasmic 1 intermediate chain 2

Q13409

Cytoplasmic dynein 1 intermediate chain 2

Alternate Names

cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein intermediate chain 2, DH IC-2, DIC74, DNCI2, dynein intermediate chain 2, cytosolic, dynein, cytoplasmic, intermediate polypeptide 2, IC2, testis tissue sperm-binding protein Li 66n

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.