Bethyl Laboratories
Rabbit anti-EFTUD2/SNRP116 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00161
TargetEFTUD2/SNRP116
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
The splicesome is the molecular machine responsible for catalyzing intron removal from pre-mRNA transcripts. The splicesome is composed of several small nuclear RNAs (snRNAs) complexed with their associated proteins [together termed snRNPs (small nuclear ribonucleoprotein)]. One of the major classes of snRNPs includes the U1, U2, U4, U5 and U6 snRNP. EFTUD2/SNRP116 is a component of the U5 snRNP. EFTUD2/SNRP116 is a GTPase that may play a role in disrupting U4/U6 helices prior to splicesome activation.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetEFTUD2/SNRP116
Antigen Species
Human
Gene ID9343
Gene Symbol
EFTUD2
Gene Name
elongation factor Tu GTP binding domain containing 2
Uniprot IDQ15029
Protein Name
116 kDa U5 small nuclear ribonucleoprotein component
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to EFTUD2/SNRP116 immobilized on solid support.
The epitope recognized by IHC-00161 maps to a region between residues 1 and 50 of human Elongation Factor Tu GTP Binding Domain Containing 2 (U5 snRNP-Specific Protein, 116 kD ) using the numbering given in entry NP_004238.2 (GeneID 9343).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00161Open
Product DatasheetPDF · IHC-00161 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00161 · Lot 1 (current lot)Open
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