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Rabbit anti-EIF2AK1 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

EIF2AK1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 580 and 630

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Eukaryotic translation initiation factor 2-alpha kinase 1 (EIF2AK1) is also known as Heme-regulated inhibitor (HRI). EIF2AK1 is regulated and inactivated by Hemin. EIF2AK1 Mediates down-regulation of protein synthesis in response to various stress conditions by the phosphorylation of eIF-2alpha at 'Ser-48' and 'Ser-51'.

27102

EIF2AK1

eukaryotic translation initiation factor 2 alpha kinase 1

Q9BQI3

Eukaryotic translation initiation factor 2-alpha kinase 1

Alternate Names

eukaryotic translation initiation factor 2-alpha kinase 1; HCR; heme regulated initiation factor 2 alpha kinase; heme sensitive initiation factor 2a kinase; heme-controlled repressor; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; heme-regulated inhibitor; heme-regulated repressor; hemin-sensitive initiation factor 2-alpha kinase; HRI

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.